Ontology highlight
ABSTRACT:
SUBMITTER: Sugawara T
PROVIDER: S-EPMC3392777 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Stem cell research & therapy 20120308 2
Induced pluripotent stem (iPS) cells, obtained from reprogramming somatic cells by ectopic expression of a defined set of transcription factors or chemicals, are expected to be used as differentiated cells for drug screening or evaluations of drug toxicity and cell replacement therapies. As pluripotent stem cells, iPS cells are similar to embryonic stem (ES) cells in morphology and marker expression. Several types of iPS cells have been generated using combinations of reprogramming molecules and ...[more]