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6-[(2-Hy-droxy-eth-yl)amino]-7H-dibenzo[de,h]quinolin-7-one.

ABSTRACT: The title compound, C(18)H(14)N(2)O(2), is a new oxoisoaporphine derivative synthesized by alkyl-ation of 6-chloro-1-aza-benzanthrone. The oxoisoaporphine fragment deviates significantly from planarity with a dihedral angle of 5.1?(1)° between the heterocycle and the remote benzene ring. The amino and oxo groups are involved in an intra-molecular N-H?O hydrogen bond, while the hy-droxy groups form inter-molecular O-H?N hydrogen bonds, which link pairs of mol-ecules into inversion dimers. In the dimer, two approximately parallel oxoisoaporphine fragments exhibit ?-? inter-actions between the aromatic rings, the shortest centroid-centroid distance being 3.649?(3)?Å.

SUBMITTER: Tang H

PROVIDER: S-EPMC3393276 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature

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6-[(2-Hy-droxy-eth-yl)amino]-7H-dibenzo[de,h]quinolin-7-one.

Tang Huang H Wang Zhi-Yu ZY Liu Yan-Cheng YC

Acta crystallographica. Section E, Structure reports online 20120602 Pt 7

The title compound, C(18)H(14)N(2)O(2), is a new oxoisoaporphine derivative synthesized by alkyl-ation of 6-chloro-1-aza-benzanthrone. The oxoisoaporphine fragment deviates significantly from planarity with a dihedral angle of 5.1 (1)° between the heterocycle and the remote benzene ring. The amino and oxo groups are involved in an intra-molecular N-H⋯O hydrogen bond, while the hy-droxy groups form inter-molecular O-H⋯N hydrogen bonds, which link pairs of mol-ecules into inversion dimers. In the ...[more]

PMID: 22807833

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