Ontology highlight
ABSTRACT:
SUBMITTER: Tobudic S
PROVIDER: S-EPMC3393440 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Tobudic Selma S Matzneller Peter P Stoiser Brigitte B Wenisch Judith Maria JM Zeitlinger Markus M Vychytil Andreas A Jaeger Walter W Boehmdorfer Michaela M Reznicek Gottfried G Burgmann Heinz H
Antimicrobial agents and chemotherapy 20120507 7
Blood and dialysate concentrations of fosfomycin were determined after intravenous and intraperitoneal application of 4 mg/liter in patients undergoing automated peritoneal dialysis. Maximum serum concentrations after intravenous (287.75 ± 86.34 mg/liter) and intraperitoneal (205.78 ± 66.78 mg/liter) administration were comparable. Ratios of intraperitoneal to systemic exposure were 1.12 (intraperitoneal administration) and 0.22 (intravenous administration), indicating good systemic exposure aft ...[more]