Ontology highlight
ABSTRACT:
SUBMITTER: Kunik V
PROVIDER: S-EPMC3394289 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Kunik Vered V Ashkenazi Shaul S Ofran Yanay Y
Nucleic acids research 20120606 Web Server issue
Antibodies are capable of specifically recognizing and binding antigens. Identification of the antigen-binding site, commonly dubbed paratope, is of high importance both for medical and biological applications. To date, the identification of antigen-binding regions (ABRs) relies on tools for the identification of complementarity-determining regions (CDRs). However, we have shown that up to 22% of the residues that actually bind the antigen fall outside the traditionally defined CDRs. The Paratom ...[more]