Ontology highlight
ABSTRACT:
SUBMITTER: Luu TD
PROVIDER: S-EPMC3394327 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Luu Tien-Dao TD Rusu Alin A Walter Vincent V Linard Benjamin B Poidevin Laetitia L Ripp Raymond R Moulinier Luc L Muller Jean J Raffelsberger Wolfgang W Wicker Nicolas N Lecompte Odile O Thompson Julie D JD Poch Olivier O Nguyen Hoan H
Nucleic acids research 20120527 Web Server issue
A major challenge in the post-genomic era is a better understanding of how human genetic alterations involved in disease affect the gene products. The KD4v (Comprehensible Knowledge Discovery System for Missense Variant) server allows to characterize and predict the phenotypic effects (deleterious/neutral) of missense variants. The server provides a set of rules learned by Induction Logic Programming (ILP) on a set of missense variants described by conservation, physico-chemical, functional and ...[more]