Ontology highlight
ABSTRACT:
SUBMITTER: Qian Z
PROVIDER: S-EPMC3396475 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Qian Zhong Z Dimitriadis Emilios K EK Edgar Rotem R Eswaramoorthy Prahathees P Adhya Sankar S
Proceedings of the National Academy of Sciences of the United States of America 20120625 28
By microscopic analysis of fluorescent-labeled GalR, a regulon-specific transcription factor in Escherichia coli, we observed that GalR is present in the cell as aggregates (one to three fluorescent foci per cell) in nongrowing cells. To investigate whether these foci represent GalR-mediated association of some of the GalR specific DNA binding sites (gal operators), we used the chromosome conformation capture (3C) method in vivo. Our 3C data demonstrate that, in stationary phase cells, many of t ...[more]