Ontology highlight
ABSTRACT:
SUBMITTER: Patel DA
PROVIDER: S-EPMC3396790 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Patel Divya A DA Rozek Laura S LS Colacino Justin A JA Van Zomeren-Dohm Adrienne A Ruffin Mack T MT Unger Elizabeth R ER Dolinoy Dana C DC Swan David C DC Onyekwuluje Juanita J DeGraffinreid Cecilia R CR Paskett Electra D ED
Journal of virological methods 20120601 1-2
Aberrant promoter methylation of biologically relevant genes in cervical cancer and uneven CpG distribution within the human papillomavirus 16 (HPV 16) enhancer region have been reported. Cervical samples and questionnaires from 151 women screened for cervical cancer in Appalachian Ohio were analyzed. Methylation was measured by bisulfite sequencing in candidate gene sites in ESR1, DCC, p16, and LINE1 elements. Among 89 HPV 16-positive women, CpG sites in the E6 promoter and enhancer regions and ...[more]