Target molecular simulations of RecA family protein filaments.
Ontology highlight
ABSTRACT:
SUBMITTER: Su ZY
PROVIDER: S-EPMC3397515 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Target molecular simulations of RecA family protein filaments.
Su Zhi-Yuan ZY Lee Wen-Jay WJ Su Wan-Sheng WS Wang Yeng-Tseng YT Wang Yeng-Tseng YT
International journal of molecular sciences 20120611 6
Modeling of the RadA family mechanism is crucial to understanding the DNA SOS repair process. In a 2007 report, the archaeal RadA proteins function as rotary motors (linker region: I71-K88) such as shown in Figure 1. Molecular simulations approaches help to shed further light onto this phenomenon. We find 11 rotary residues (R72, T75-K81, M84, V86 and K87) and five zero rotary residues (I71, K74, E82, R83 and K88) in the simulations. Inclusion of our simulations may help to understand the RadA f ...[more]
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