TB and HIV Therapeutics: Pharmacology Research Priorities.
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ABSTRACT:
SUBMITTER: Dooley KE
PROVIDER: S-EPMC3398575 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
TB and HIV Therapeutics: Pharmacology Research Priorities.
Dooley Kelly E KE Kim Peter S PS Williams Sharon D SD Hafner Richard R
AIDS research and treatment 20120705
An unprecedented number of investigational drugs are in the development pipeline for the treatment of tuberculosis. Among patients with tuberculosis, co-infection with HIV is common, and concurrent treatment of tuberculosis and HIV is now the standard of care. To ensure that combinations of anti-tuberculosis drugs and antiretrovirals are safe and are tested at doses most likely to be effective, selected pharmacokinetic studies based on knowledge of their metabolic pathways and their capacity to ...[more]
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