Ontology highlight
ABSTRACT:
SUBMITTER: Coco M
PROVIDER: S-EPMC3402282 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Coco Maria M Pullman James J Cohen Hillel W HW Lee Sally S Shapiro Craig C Solorzano Clemencia C Greenstein Stuart S Glicklich Daniel D
Journal of the American Society of Nephrology : JASN 20120712 8
Bisphosphonates may prevent or treat the bone loss promoted by the immunosuppressive regimens used in renal transplantation. Risedronate is a commonly used third-generation amino-bisphosphonate, but little is known about its effects on the bone health of renal transplant recipients. We randomly assigned 42 new living-donor kidney recipients to either 35 mg of risedronate weekly or placebo for 12 months. We obtained bone biopsies at the time of renal transplant and after 12 months of protocol tre ...[more]