Actin in hair cells and hearing loss.
Ontology highlight
ABSTRACT:
SUBMITTER: Drummond MC
PROVIDER: S-EPMC3403717 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Publications
Actin in hair cells and hearing loss.
Drummond Meghan C MC Belyantseva Inna A IA Friderici Karen H KH Friedman Thomas B TB
Hearing research 20111213 1-2
Hereditary deafness is genetically heterogeneous such that mutations of many different genes can cause hearing loss. This review focuses on the evidence and implications that several of these deafness genes encode actin-interacting proteins or actin itself. There is a growing appreciation of the contribution of the actin interactome in stereocilia development, maintenance, mechanotransduction and malfunction of the auditory system. ...[more]
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