Ontology highlight
ABSTRACT:
SUBMITTER: Fogel JM
PROVIDER: S-EPMC3404155 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Journal of acquired immune deficiency syndromes (1999) 20120801 5
First-line antiretroviral treatment regimens in resource-limited settings used in breastfeeding mothers often include stavudine (d4T). Limited data describing d4T concentrations in breast milk are available. We analyzed d4T concentrations in 52 mother-infant pairs using ultra-performance liquid chromatography-tandem mass spectrometry (lower limit of quantification: 5 ng/mL in plasma, 20 ng/mL in breast milk). Median (interquartile range) d4T concentrations were 86 (36-191) ng/mL in maternal plas ...[more]