Ontology highlight
ABSTRACT:
SUBMITTER: El-Sayed Moustafa JS
PROVIDER: S-EPMC3406755 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
El-Sayed Moustafa Julia S JS Eleftherohorinou Hariklia H de Smith Adam J AJ Andersson-Assarsson Johanna C JC Alves Alexessander Couto AC Hadjigeorgiou Eleni E Walters Robin G RG Asher Julian E JE Bottolo Leonardo L Buxton Jessica L JL Sladek Rob R Meyre David D Dina Christian C Visvikis-Siest Sophie S Jacobson Peter P Sjöström Lars L Carlsson Lena M S LM Walley Andrew A Falchi Mario M Froguel Philippe P Blakemore Alexandra I F AI Coin Lachlan J M LJ
Human molecular genetics 20120516 16
Variable number tandem repeats (VNTRs) constitute a relatively under-examined class of genomic variants in the context of complex disease because of their sequence complexity and the challenges in assaying them. Recent large-scale genome-wide copy number variant mapping and association efforts have highlighted the need for improved methodology for association studies using these complex polymorphisms. Here we describe the in-depth investigation of a complex region on chromosome 8p21.2 encompassi ...[more]