Ontology highlight
ABSTRACT:
SUBMITTER: Ao A
PROVIDER: S-EPMC3407188 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Ao Ada A Hao Jijun J Hopkins Corey R CR Hong Charles C CC
PloS one 20120727 7
The possibility of using cell-based therapeutics to treat cardiac failure has generated significant interest since the initial introduction of stem cell-based technologies. However, the methods to quickly and robustly direct stem cell differentiation towards cardiac cell types have been limited by a reliance on recombinant growth factors to provide necessary biological cues. We report here the use of dorsomorphin homologue 1 (DMH1), a second-generation small molecule BMP inhibitor based on dorso ...[more]