Role of ERCC5 polymorphism in risk of hepatocellular carcinoma.
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ABSTRACT:
SUBMITTER: Yoon AJ
PROVIDER: S-EPMC3408063 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Publications
Role of ERCC5 polymorphism in risk of hepatocellular carcinoma.
Yoon Angela J AJ Kuo Wu-Hsien WH Lin Chiao-Wen CW Yang Shun-Fa SF
Oncology letters 20110610 5
Excision repair cross‑complementing rodent repair deficiency, complementation group 5 (ERCC5, XPG) is a key molecule in DNA damage repair. We analyzed the contribution of ERCC5 rs751402 polymorphism in increased susceptibility to hepatocellular carcinoma (HCC). A total of 96 patients diagnosed with HCC and 336 healthy controls provided blood samples for analysis of rs751402 genotypes. Demographic data and information on habitual use of tobacco and alcohol were collected. After adjusting for cova ...[more]
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