Ontology highlight
ABSTRACT:
SUBMITTER: Lim JC
PROVIDER: S-EPMC3408158 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Lim Jung Chae JC Gruschus James M JM Ghesquière Bart B Kim Geumsoo G Piszczek Grzegorz G Tjandra Nico N Levine Rodney L RL
The Journal of biological chemistry 20120601 30
Methionine sulfoxide reductase A is an essential enzyme in the antioxidant system which scavenges reactive oxygen species through cyclic oxidation and reduction of methionine and methionine sulfoxide. The cytosolic form of the enzyme is myristoylated, but it is not known to translocate to membranes, and the function of myristoylation is not established. We compared the biochemical and biophysical properties of myristoylated and nonmyristoylated mouse methionine sulfoxide reductase A. These were ...[more]