An olfactory subsystem that mediates high-sensitivity detection of volatile amines.
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ABSTRACT:
SUBMITTER: Pacifico R
PROVIDER: S-EPMC3408605 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Publications
An olfactory subsystem that mediates high-sensitivity detection of volatile amines.
Pacifico Rodrigo R Dewan Adam A Cawley Dillon D Guo Caiying C Bozza Thomas T
Cell reports 20120628 1
Olfactory stimuli are detected by over 1,000 odorant receptors in mice, with each receptor being mapped to specific glomeruli in the olfactory bulb. The trace amine-associated receptors (TAARs) are a small family of evolutionarily conserved olfactory receptors whose contribution to olfaction remains enigmatic. Here, we show that a majority of the TAARs are mapped to a discrete subset of glomeruli in the dorsal olfactory bulb of the mouse. This TAAR projection is distinct from the previously desc ...[more]
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