Ontology highlight
ABSTRACT:
SUBMITTER: Moore LE
PROVIDER: S-EPMC3412648 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Oncogenesis 20120625
Array comparative genomic hybridization was used to identify copy number alterations in clear cell renal cell carcinoma (ccRCC) patient tumors to identify associations with patient/clinical characteristics. Of 763 ccRCC patients, 412 (54%) provided frozen biopsies. Clones were analyzed for significant copy number differences, adjusting for multiple comparisons and covariates in multivariate analyses. Frequent alterations included losses on: 3p (92.2%), 14q (46.8%), 8p (38.1%), 4q (35.4%), 9p (32 ...[more]