Ontology highlight
ABSTRACT:
SUBMITTER: Collingridge PW
PROVIDER: S-EPMC3413523 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
Collingridge Peter W PW Kelly Steven S
BMC bioinformatics 20120530
<h4>Background</h4>The generation of multiple sequence alignments (MSAs) is a crucial step for many bioinformatic analyses. Thus improving MSA accuracy and identifying potential errors in MSAs is important for a wide range of post-genomic research. We present a novel method called MergeAlign which constructs consensus MSAs from multiple independent MSAs and assigns an alignment precision score to each column.<h4>Results</h4>Using conventional benchmark tests we demonstrate that on average MergeA ...[more]