Ontology highlight
ABSTRACT:
SUBMITTER: Schenke-Layland K
PROVIDER: S-EPMC3414535 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Schenke-Layland Katja K Nsair Ali A Van Handel Ben B Angelis Ekaterini E Gluck Jessica M JM Votteler Miriam M Goldhaber Joshua I JI Mikkola Hanna K HK Kahn Michael M Maclellan William R WR
Biomaterials 20110122 11
Stem or progenitor cell populations are often established in unique niche microenvironments that regulate cell fate decisions. Although niches have been shown to be critical for the normal development of several tissues, their role in the cardiovascular system is poorly understood. In this study, we characterized the cardiovascular progenitor cell (CPC) niche in developing human and mouse hearts, identifying signaling pathways and extracellular matrix (ECM) proteins that are crucial for CPC main ...[more]