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Complete genome sequence of bacteriophage BC-611 specifically infecting Enterococcus faecalis strain NP-10011.

ABSTRACT: Enterococcus faecalis is an opportunistic pathogen that causes serious infections in humans and animals and is also an important bacterium for dairy and probiotic supplement production. Therefore, bacteriophages infecting E. faecalis may be useful for phage therapy against multidrug-resistant strains or may threaten industrial fermentation. We isolated a virulent Siphoviridae bacteriophage, BC-611, specifically infecting E. faecalis strain NP-10011 but not infecting other E. faecalis strains or other enterococci. Although the genome sequence of BC-611 resembled that of enterococcal bacteriophage SAP6, BC-611 was marked by its narrow host specificity.

SUBMITTER: Horiuchi T

PROVIDER: S-EPMC3416177 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature

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Complete genome sequence of bacteriophage BC-611 specifically infecting Enterococcus faecalis strain NP-10011.

Horiuchi Tomohiro T Sakka Makiko M Hayashi Atsushi A Shimada Takashi T Kimura Tetsuya T Sakka Kazuo K

Journal of virology 20120901 17

Enterococcus faecalis is an opportunistic pathogen that causes serious infections in humans and animals and is also an important bacterium for dairy and probiotic supplement production. Therefore, bacteriophages infecting E. faecalis may be useful for phage therapy against multidrug-resistant strains or may threaten industrial fermentation. We isolated a virulent Siphoviridae bacteriophage, BC-611, specifically infecting E. faecalis strain NP-10011 but not infecting other E. faecalis strains or ...[more]

PMID: 22879611

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