Ontology highlight
ABSTRACT:
SUBMITTER: Xu J
PROVIDER: S-EPMC3418377 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Xu Jing J Shu Zhanyong Z King Stephen J SJ Gross Steven P SP
Traffic (Copenhagen, Denmark) 20120703 9
Microtubule-based molecular motors often work in small groups to transport cargos in cells. A key question in understanding transport (and its regulation in vivo) is to identify the sensitivity of multiple-motor-based motion to various single molecule properties. Whereas both single-motor travel distance and microtubule binding rate have been demonstrated to contribute to cargo travel, the role of single-motor velocity is yet to be explored. Here, we recast a previous theoretical study, and make ...[more]