Identification of heme propionate vibrational modes in the resonance Raman spectra of cytochrome c oxidase.
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ABSTRACT:
SUBMITTER: Egawa T
PROVIDER: S-EPMC3418657 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
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Identification of heme propionate vibrational modes in the resonance Raman spectra of cytochrome c oxidase.
Egawa Tsuyoshi T Lee Hyun Ju HJ Ji Hong H Gennis Robert B RB Yeh Syun-Ru SR Rousseau Denis L DL
Analytical biochemistry 20090627 1
The propionate groups of heme a and a(3) in cytochrome c oxidase (CcO) have been postulated to mediate both the electron and proton transfer within the enzyme. To establish structural markers for the propionate groups, their associated vibrational modes were identified in the resonance Raman spectra of CcO from bovine (bCcO) and Rhodobacter sphaeroides (RsCcO). The distinction between the modes from the propionates of heme a and heme a(3), as well as those from the propionates on the pyrrole rin ...[more]
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