Dataset Information

Lost letter measure of variation in altruistic behaviour in 20 neighbourhoods.

ABSTRACT: Altruistic behaviour varies across human populations and this variation is likely to be partly explained by variation in the ecological context of the populations. We hypothesise that area level socio-economic characteristics will determine the levels of altruism found in individuals living in an area and we use a lost letter experiment to measure altruism across 20 neighbourhoods with a wide range of income deprivation scores in London, UK. The results show a strong negative effect of neighbourhood income deprivation on altruistic behaviour, with letters dropped in the poorest neighbourhoods having 91% lower odds of being returned than letters dropped in the wealthiest neighbourhoods. We suggest that measures of altruism are strongly context dependant.

SUBMITTER: Holland J

PROVIDER: S-EPMC3419711 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

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Lost letter measure of variation in altruistic behaviour in 20 neighbourhoods.

Holland Jo J Silva Antonio S AS Mace Ruth R

PloS one 20120815 8

Altruistic behaviour varies across human populations and this variation is likely to be partly explained by variation in the ecological context of the populations. We hypothesise that area level socio-economic characteristics will determine the levels of altruism found in individuals living in an area and we use a lost letter experiment to measure altruism across 20 neighbourhoods with a wide range of income deprivation scores in London, UK. The results show a strong negative effect of neighbour ...[more]

PMID: 22905250

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Project description:Low-contrast letter acuity (LCLA) has emerged as the leading outcome measure to assess visual disability in multiple sclerosis (MS) research. As visual dysfunction is one of the most common manifestations of MS, sensitive visual outcome measures are important in examining the effect of treatment. Low-contrast acuity captures visual loss not seen in high-contrast visual acuity (HCVA) measurements. These issues are addressed by the MS Outcome Assessments Consortium (MSOAC), including representatives from advocacy organizations, Food and Drug Administration (FDA), European Medicines Agency (EMA), National Institute of Neurological Disorders and Stroke (NINDS), academic institutions, and industry partners along with persons living with MS. MSOAC goals are acceptance and qualification by regulators of performance outcomes that are highly reliable and valid, practical, cost-effective, and meaningful to persons with MS. A critical step is elucidation of clinically relevant benchmarks, well-defined degrees of disability, and gradients of change that are clinically meaningful. This review shows that MS and disease-free controls have similar median HCVA, while MS patients have significantly lower LCLA. Deficits in LCLA and vision-specific quality of life are found many years after an episode of acute optic neuritis, even when HCVA has recovered. Studies reveal correlations between LCLA and the Expanded Disability Status Score (EDSS), Multiple Sclerosis Functional Composite (MSFC), retinal nerve fiber layer (RNFL) and ganglion cell layer plus inner plexiform layer (GCL + IPL) thickness on optical coherence tomography (OCT), brain magnetic resonance imaging (MRI), visual evoked potential (VEP), electroretinogram (ERG), pupillary function, and King-Devick testing. This review also concludes that a 7-point change in LCLA is clinically meaningful. The overall goal of this review is to describe and characterize the LCLA metric for research and clinical use among persons with MS.

Dataset Information

Lost letter measure of variation in altruistic behaviour in 20 neighbourhoods.

Publications

Lost letter measure of variation in altruistic behaviour in 20 neighbourhoods.

Similar Datasets

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