Evolution of the FGF Gene Family.
Ontology highlight
ABSTRACT:
SUBMITTER: Oulion S
PROVIDER: S-EPMC3420111 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Evolution of the FGF Gene Family.
Oulion Silvan S Bertrand Stephanie S Escriva Hector H
International journal of evolutionary biology 20120807
Fibroblast Growth Factors (FGFs) are small proteins generally secreted, acting through binding to transmembrane tyrosine kinase receptors (FGFRs). Activation of FGFRs triggers several cytoplasmic cascades leading to the modification of cell behavior. FGFs play critical roles in a variety of developmental and physiological processes. Since their discovery in mammals, FGFs have been found in many metazoans and some arthropod viruses. Efforts have been previously made to decipher the evolutionary h ...[more]
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