Unknown

Dataset Information

0

Gamma knife radiosurgery for mesial temporal lobe epilepsy.


ABSTRACT: Many patients with mesial temporal lobe epilepsy continue to have seizures despite medical therapy. For these patients, one recourse is surgical resection of the mesial temporal lobe, with its attendant risks. Noninvasive treatment with Gamma Knife radiosurgery is under active investigation as a possible alternative to open surgery. Accumulated evidence from multiple studies shows radiosurgery to be comparable in outcomes to surgical resection. A definitive randomized, controlled trial, the Radiosurgery or Open Surgery for Epilepsy (ROSE) trial, is currently underway, and further investigation of this promising treatment is crucial in our advancement of alternative therapies to treat refractory epilepsy.

SUBMITTER: Rolston JD 

PROVIDER: S-EPMC3420694 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature

altmetric image

Publications

Gamma knife radiosurgery for mesial temporal lobe epilepsy.

Rolston John D JD   Quigg Mark M   Barbaro Nicholas M NM  

Epilepsy research and treatment 20111029


Many patients with mesial temporal lobe epilepsy continue to have seizures despite medical therapy. For these patients, one recourse is surgical resection of the mesial temporal lobe, with its attendant risks. Noninvasive treatment with Gamma Knife radiosurgery is under active investigation as a possible alternative to open surgery. Accumulated evidence from multiple studies shows radiosurgery to be comparable in outcomes to surgical resection. A definitive randomized, controlled trial, the Radi  ...[more]

Similar Datasets

| S-EPMC3519361 | biostudies-literature
| S-EPMC4569650 | biostudies-literature
2010-06-11 | E-GEOD-6773 | biostudies-arrayexpress
2007-01-23 | GSE6773 | GEO
2007-01-23 | E-GEOD-6771 | biostudies-arrayexpress
| S-EPMC6413861 | biostudies-literature
2007-01-23 | GSE6771 | GEO
2012-12-01 | E-GEOD-25453 | biostudies-arrayexpress
| S-EPMC4867275 | biostudies-literature
| S-EPMC5877322 | biostudies-literature