Ontology highlight
ABSTRACT:
SUBMITTER: Berenguer M
PROVIDER: S-EPMC3421477 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Berenguer Marina M López-Labrador F Xavier FX
Biologics : targets & therapy 20120803
Chronic hepatitis C virus infection is an important public health problem, and the standard treatment (combination of pegylated interferon-α and ribavirin) has an effectiveness rate of only 40%-50%. Novel virus-specific drugs have recently been designed, and multiple compounds are under development. The approval for the clinical use of direct-acting antivirals in 2011 (boceprevir [BOC] and telaprevir, viral NS3 protease inhibitors) has increased recovery rates by up to 70%. Therefore, a highly e ...[more]