Ontology highlight
ABSTRACT:
SUBMITTER: Carraway HE
PROVIDER: S-EPMC3422075 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Carraway Hetty E HE Wang Shelun S Blackford Amanda A Guo Mingzho M Powers Penny P Jeter Stacie S Davidson Nancy E NE Argani Pedram P Terrell Kyle K Herman James G JG Lange Julie R JR
Breast cancer research and treatment 20080411 2
<h4>Purpose</h4>Promoter methylation of tumor suppressor genes in histologically negative sentinel lymph nodes (HNSN) of early stage breast cancer patients has not been extensively studied. This study evaluates the methylation frequency and pattern in HNSN to determine if detection of hypermethylation of one or more genes is associated with an increased recurrence risk in node negative breast cancer.<h4>Experimental design</h4>In 1998, a prospective study of patients with early stage breast canc ...[more]