Ontology highlight
ABSTRACT:
SUBMITTER: Hu L
PROVIDER: S-EPMC3422752 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Hu Liya L Crawford Sue E SE Hyser Joseph M JM Estes Mary K MK Prasad B V Venkataram BV
Current opinion in virology 20120711 4
The replication of rotavirus is a complex process that is orchestrated by an exquisite interplay between the rotavirus non-structural and structural proteins. Subsequent to particle entry and genome transcription, the non-structural proteins coordinate and regulate viral mRNA translation and the formation of electron-dense viroplasms that serve as exclusive compartments for genome replication, genome encapsidation and capsid assembly. In addition, non-structural proteins are involved in antagoni ...[more]