Ontology highlight
ABSTRACT:
SUBMITTER: Huber D
PROVIDER: S-EPMC3425380 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
Huber Daniel D Petreanu Leopoldo L Ghitani Nima N Ranade Sachin S Hromádka Tomás T Mainen Zach Z Svoboda Karel K
Nature 20080101 7174
Electrical microstimulation can establish causal links between the activity of groups of neurons and perceptual and cognitive functions. However, the number and identities of neurons microstimulated, as well as the number of action potentials evoked, are difficult to ascertain. To address these issues we introduced the light-gated algal channel channelrhodopsin-2 (ChR2) specifically into a small fraction of layer 2/3 neurons of the mouse primary somatosensory cortex. ChR2 photostimulation in viv ...[more]