Ontology highlight
ABSTRACT:
SUBMITTER: Lachance J
PROVIDER: S-EPMC3426505 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Lachance Joseph J Vernot Benjamin B Elbers Clara C CC Ferwerda Bart B Froment Alain A Bodo Jean-Marie JM Lema Godfrey G Fu Wenqing W Nyambo Thomas B TB Rebbeck Timothy R TR Zhang Kun K Akey Joshua M JM Tishkoff Sarah A SA
Cell 20120726 3
To reconstruct modern human evolutionary history and identify loci that have shaped hunter-gatherer adaptation, we sequenced the whole genomes of five individuals in each of three different hunter-gatherer populations at > 60× coverage: Pygmies from Cameroon and Khoesan-speaking Hadza and Sandawe from Tanzania. We identify 13.4 million variants, substantially increasing the set of known human variation. We found evidence of archaic introgression in all three populations, and the distribution of ...[more]