Dataset Information

Dietary fiber, carbohydrate quality and quantity, and mortality risk of individuals with diabetes mellitus.

ABSTRACT:

Background

Dietary fiber, carbohydrate quality and quantity are associated with mortality risk in the general population. Whether this is also the case among diabetes patients is unknown.

Objective

To assess the associations of dietary fiber, glycemic load, glycemic index, carbohydrate, sugar, and starch intake with mortality risk in individuals with diabetes.

Methods

This study was a prospective cohort study among 6,192 individuals with confirmed diabetes mellitus (mean age of 57.4 years, and median diabetes duration of 4.4 years at baseline) from the European Prospective Investigation into Cancer and Nutrition (EPIC). Dietary intake was assessed at baseline (1992-2000) with validated dietary questionnaires. Cox proportional hazards analysis was performed to estimate hazard ratios (HRs) for all-cause and cardiovascular mortality, while adjusting for CVD-related, diabetes-related, and nutritional factors.

Results

During a median follow-up of 9.2 y, 791 deaths were recorded, 306 due to CVD. Dietary fiber was inversely associated with all-cause mortality risk (adjusted HR per SD increase, 0.83 [95% CI, 0.75-0.91]) and CVD mortality risk (0.76[0.64-0.89]). No significant associations were observed for glycemic load, glycemic index, carbohydrate, sugar, or starch. Glycemic load (1.42[1.07-1.88]), carbohydrate (1.67[1.18-2.37]) and sugar intake (1.53[1.12-2.09]) were associated with an increased total mortality risk among normal weight individuals (BMI?25 kg/m(2); 22% of study population) but not among overweight individuals (P interaction?0.04). These associations became stronger after exclusion of energy misreporters.

Conclusions

High fiber intake was associated with a decreased mortality risk. High glycemic load, carbohydrate and sugar intake were associated with an increased mortality risk in normal weight individuals with diabetes.

SUBMITTER: Burger KN

PROVIDER: S-EPMC3426551 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

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Publications

Dietary fiber, carbohydrate quality and quantity, and mortality risk of individuals with diabetes mellitus.

Burger Koert N J KN Beulens Joline W J JW van der Schouw Yvonne T YT Sluijs Ivonne I Spijkerman Annemieke M W AM Sluik Diewertje D Boeing Heiner H Kaaks Rudolf R Teucher Birgit B Dethlefsen Claus C Overvad Kim K Tjønneland Anne A Kyrø Cecilie C Barricarte Aurelio A Bendinelli Benedetta B Krogh Vittorio V Tumino Rosario R Sacerdote Carlotta C Mattiello Amalia A Nilsson Peter M PM Orho-Melander Marju M Rolandsson Olov O Huerta José María JM Crowe Francesca F Allen Naomi N Nöthlings Ute U

PloS one 20120823 8

<h4>Background</h4>Dietary fiber, carbohydrate quality and quantity are associated with mortality risk in the general population. Whether this is also the case among diabetes patients is unknown.<h4>Objective</h4>To assess the associations of dietary fiber, glycemic load, glycemic index, carbohydrate, sugar, and starch intake with mortality risk in individuals with diabetes.<h4>Methods</h4>This study was a prospective cohort study among 6,192 individuals with confirmed diabetes mellitus (mean ag ...[more]

PMID: 22927948

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Dataset Information

Dietary fiber, carbohydrate quality and quantity, and mortality risk of individuals with diabetes mellitus.

Background

Objective

Methods

Results

Conclusions

Publications

Dietary fiber, carbohydrate quality and quantity, and mortality risk of individuals with diabetes mellitus.

Similar Datasets

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