Ontology highlight
ABSTRACT:
SUBMITTER: Wirtz M
PROVIDER: S-EPMC3431704 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Wirtz Markus M Beard Katherine F M KF Lee Chun Pong CP Boltz Achim A Schwarzländer Markus M Fuchs Christopher C Meyer Andreas J AJ Heeg Corinna C Sweetlove Lee J LJ Ratcliffe R George RG Hell Rüdiger R
The Journal of biological chemistry 20120622 33
Cysteine synthesis is catalyzed by serine acetyltransferase (SAT) and O-acetylserine (thiol) lyase (OAS-TL) in the cytosol, plastids, and mitochondria of plants. Biochemical analyses of recombinant plant SAT and OAS-TL indicate that the reversible association of the proteins in the cysteine synthase complex (CSC) controls cellular sulfur homeostasis. However, the relevance of CSC formation in each compartment for flux control of cysteine synthesis remains controversial. Here, we demonstrate the ...[more]