Stromal-to-epithelial transition during postpartum endometrial regeneration.
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ABSTRACT:
SUBMITTER: Huang CC
PROVIDER: S-EPMC3433810 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Stromal-to-epithelial transition during postpartum endometrial regeneration.
Huang Cheng-Chiu CC Orvis Grant D GD Wang Ying Y Behringer Richard R RR
PloS one 20120827 8
Endometrium is the inner lining of the uterus which is composed of epithelial and stromal tissue compartments enclosed by the two smooth muscle layers of the myometrium. In women, much of the endometrium is shed and regenerated each month during the menstrual cycle. Endometrial regeneration also occurs after parturition. The cellular mechanisms that regulate endometrial regeneration are still poorly understood. Using genetic fate-mapping in the mouse, we found that the epithelial compartment of ...[more]
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