Ontology highlight
ABSTRACT:
SUBMITTER: Maling N
PROVIDER: S-EPMC3435399 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Maling Nicholas N Hashemiyoon Rowshanak R Foote Kelly D KD Okun Michael S MS Sanchez Justin C JC
PloS one 20120906 9
Tourette syndrome (TS) is an idiopathic, childhood-onset neuropsychiatric disorder, which is marked by persistent multiple motor and phonic tics. The disorder is highly disruptive and in some cases completely debilitating. For those with severe, treatment-refractory TS, deep brain stimulation (DBS) has emerged as a possible option, although its mechanism of action is not fully understood. We performed a longitudinal study of the effects of DBS on TS symptomatology while concomitantly examining n ...[more]