Ontology highlight
ABSTRACT:
SUBMITTER: Ruff BM
PROVIDER: S-EPMC3435518 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Ruff Bettina M BM Bräse S S O'Connor Sarah E SE
Tetrahedron letters 20120201 9
The promiscuity of the enzyme norcoclaurine synthase is described. This biocatalyst yielded a diverse array of substituted tetrahydroisoquinolines by cyclizing dopamine with various acetaldehydes in a Pictet-Spengler reaction. This enzymatic reaction may provide a biocatalytic route to a range of tetrahydroisoquinoline alkaloids. ...[more]