Ontology highlight
ABSTRACT:
SUBMITTER: Chang A
PROVIDER: S-EPMC3439557 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Chang Anthony A Moore Jocelyn M JM Cowan Michelle L ML Josephson Michelle A MA Chon W James WJ Sciammas Roger R Du Zeying Z Marino Susana R SR Meehan Shane M SM Millis Michael M David Michael Z MZ Williams James W JW Chong Anita S AS
Transplant international : official journal of the European Society for Organ Transplantation 20120717 10
The contribution of T cells and graft-reactive antibodies to acute allograft rejection is widely accepted, but the role of graft-infiltrating B and plasma cells is controversial. We examined 56 consecutive human renal transplant biopsies classified by Banff schema into T-cell-mediated (N = 21), antibody-mediated (N = 18), and mixed (N = 17) acute rejection, using standard immunohistochemistry for CD3, CD20, CD138, and CD45. In a predominantly African-American population (75%), neither Banff clas ...[more]