Diversity of 5S rRNA genes within individual prokaryotic genomes.
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ABSTRACT:
SUBMITTER: Pei A
PROVIDER: S-EPMC3439594 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Publications
Diversity of 5S rRNA genes within individual prokaryotic genomes.
Pei Anna A Li Hongru H Oberdorf William E WE Alekseyenko Alexander V AV Parsons Tamasha T Yang Liying L Gerz Erika A EA Lee Peng P Xiang Charlie C Nossa Carlos W CW Pei Zhiheng Z
FEMS microbiology letters 20120802 1
We examined intragenomic variation of paralogous 5S rRNA genes to evaluate the concept of ribosomal constraints. In a dataset containing 1161 genomes from 779 unique species, 96 species exhibited > 3% diversity. Twenty-seven species with > 10% diversity contained a total of 421 mismatches between all pairs of the most dissimilar copies of 5S rRNA genes. The large majority (401 of 421) of the diversified positions were conserved at the secondary structure level. The high diversity was associated ...[more]
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