Ontology highlight
ABSTRACT:
SUBMITTER: Rusu M
PROVIDER: S-EPMC3440181 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
Rusu Mirabela M Starosolski Zbigniew Z Wahle Manuel M Rigort Alexander A Wriggers Willy W
Journal of structural biology 20120313 2
The molecular graphics program Sculptor and the command-line suite Situs are software packages for the integration of biophysical data across spatial resolution scales. Herein, we provide an overview of recently developed tools relevant to cryo-electron tomography (cryo-ET), with an emphasis on functionality supported by Situs 2.7.1 and Sculptor 2.1.1. We describe a work flow for automatically segmenting filaments in cryo-ET maps including denoising, local normalization, feature detection, and t ...[more]