Ontology highlight
ABSTRACT:
SUBMITTER: Jakubowski JA
PROVIDER: S-EPMC3440581 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Jakubowski Joseph A JA Riesmeyer Jeffrey S JS Close Sandra L SL Leishman Amy G AG Erlinge David D
Cardiovascular therapeutics 20110217 4
Prasugrel, a third-generation thienopyridine antiplatelet agent, demonstrated superior efficacy to clopidogrel but with an increased risk of bleeding in the phase III pivotal registration Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition with Prasugrel-Thrombolysis in Myocardial Infarction (TRITON-TIMI 38). This article reviews and discusses select components of a large literature of prasugrel data that has emerged since the TRITON-TIMI 38 (TRITON) study prima ...[more]