Ontology highlight
ABSTRACT:
SUBMITTER: Glazko GV
PROVIDER: S-EPMC3441527 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Glazko Galina V GV Zybailov Boris L BL Rogozin Igor B IB
PloS one 20120913 9
Among thousands of long non-coding RNAs (lncRNAs) only a small subset is functionally characterized and the functional annotation of lncRNAs on the genomic scale remains inadequate. In this study we computationally characterized two functionally different parts of human lncRNAs transcriptome based on their ability to bind the polycomb repressive complex, PRC2. This classification is enabled by the fact that while all lncRNAs constitute a diverse set of sequences, the classes of PRC2-binding and ...[more]