Ontology highlight
ABSTRACT:
SUBMITTER: Youn H
PROVIDER: S-EPMC344431 | biostudies-literature | 2004 Mar
REPOSITORIES: biostudies-literature
Youn Hwan H Kerby Robert L RL Conrad Mary M Roberts Gary P GP
Journal of bacteriology 20040301 5
CooA is a heme-containing transcriptional activator that enables Rhodospirillum rubrum to sense and grow on CO as a sole energy source. We have identified a number of CooA homologs through database searches, expressed these heterologously in Escherichia coli, and monitored their ability to respond to CO in vivo. Further in vitro analysis of two CooA homologs from Azotobacter vinelandii and Carboxydothermus hydrogenoformans corroborated the in vivo data by revealing the ability of CO to bind to t ...[more]