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Impact of sex hormonal changes on tension-type headache and migraine: a cross-sectional population-based survey in 2,600 women.


ABSTRACT: Sex hormones have some implications on headaches. The objective of the study was to investigate the effects of hormonal changes comparatively on tension-type headache (TTH) and migraine, in a population-based sample. A nationwide face-to-face prevalence study was conducted using a structured electronic questionnaire. 54.3 % of the migraineurs reported that the probability of experiencing headache during menstruation was high, whereas 3.9 % had headache only during menstruation. Forward logistic regression analysis revealed that menstruation was a significant trigger for migraine in comparison to TTH. On the other hand, nearly double the number of TTH sufferers reported "pure menstrual headache" compared to migraineurs (p = 0.02). Menstrual headaches caused significantly higher MIDAS grades. One-third of the definite migraineurs reported improvement during pregnancy and oral contraceptives significantly worsened migraine. Menopause had a slight improving effect on migraine compared to TTH. Sex hormonal changes have major impacts particularly on migraine; however, the effects of hormonal fluctuations on TTH should not be underestimated.

SUBMITTER: Karl? N 

PROVIDER: S-EPMC3444543 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature

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Impact of sex hormonal changes on tension-type headache and migraine: a cross-sectional population-based survey in 2,600 women.

Karlı Necdet N   Baykan Betül B   Ertaş Mustafa M   Zarifoğlu Mehmet M   Siva Aksel A   Saip Sabahattin S   Ozkaya Güven G   Onal Ayşe Emel AE  

The journal of headache and pain 20120831 7


Sex hormones have some implications on headaches. The objective of the study was to investigate the effects of hormonal changes comparatively on tension-type headache (TTH) and migraine, in a population-based sample. A nationwide face-to-face prevalence study was conducted using a structured electronic questionnaire. 54.3 % of the migraineurs reported that the probability of experiencing headache during menstruation was high, whereas 3.9 % had headache only during menstruation. Forward logistic  ...[more]

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