Ontology highlight
ABSTRACT:
SUBMITTER: Guerra SG
PROVIDER: S-EPMC3446495 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Arthritis research & therapy 20120529 3
Systemic lupus erythematosus (SLE) is an autoimmune disease with a strong genetic component and is characterized by chronic inflammation and the production of anti-nuclear auto-antibodies. In the era of genome-wide association studies (GWASs), elucidating the genetic factors present in SLE has been a very successful endeavor; 28 confirmed disease susceptibility loci have been mapped. In this review, we summarize the current understanding of the genetics of lupus and focus on the strongest associ ...[more]