Flow loading induces oscillatory trajectories in a bloodstream parasite.
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ABSTRACT:
SUBMITTER: Uppaluri S
PROVIDER: S-EPMC3446674 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Publications
Flow loading induces oscillatory trajectories in a bloodstream parasite.
Uppaluri Sravanti S Heddergott Niko N Stellamanns Eric E Herminghaus Stephan S Zöttl Andreas A Stark Holger H Engstler Markus M Pfohl Thomas T
Biophysical journal 20120901 6
The dynamics of isolated microswimmers are studied in bounded flow using the African trypanosome, a unicellular parasite, as the model organism. With the help of a microfluidics platform, cells are subjected to flow and found to follow an oscillatory path that is well fit by a sine wave. The frequency and amplitudes of the oscillatory trajectories are dependent on the flow velocity and cell orientation. When traveling in such a manner, trypanosomes orient upstream while downstream-facing cells t ...[more]
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