Ontology highlight
ABSTRACT:
SUBMITTER: Halavaty AS
PROVIDER: S-EPMC3447402 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Halavaty Andrei S AS Kim Youngchang Y Minasov George G Shuvalova Ludmilla L Dubrovska Ievgeniia I Winsor James J Zhou Min M Onopriyenko Olena O Skarina Tatiana T Papazisi Leka L Kwon Keehwan K Peterson Scott N SN Joachimiak Andrzej A Savchenko Alexei A Anderson Wayne F WF
Acta crystallographica. Section D, Biological crystallography 20120913 Pt 10
Some bacterial type II fatty-acid synthesis (FAS II) enzymes have been shown to be important candidates for drug discovery. The scientific and medical quest for new FAS II protein targets continues to stimulate research in this field. One of the possible additional candidates is the acyl-carrier-protein synthase (AcpS) enzyme. Its holo form post-translationally modifies the apo form of an acyl carrier protein (ACP), which assures the constant delivery of thioester intermediates to the discrete e ...[more]