Ontology highlight
ABSTRACT:
SUBMITTER: Fischetti VA
PROVIDER: S-EPMC3448103 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Bacteriophage 20110701 4
In the billion years that bacteriophage (or phage) have existed together with bacteria the phage have evolved systems that may be exploited for our benefit. One of these is the lytic system used by the phage to release their progeny from an infected bacterium. Endolysins (or lysins) are highly evolved enzymes in the lytic system produced to cleave essential bonds in the bacterial cell wall peptidoglycan for progeny release. Small quantities of purified recombinant lysin added externally to gram- ...[more]