Ontology highlight
ABSTRACT:
SUBMITTER: Shibayama Y
PROVIDER: S-EPMC3448104 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Shibayama Youtaro Y Dabbs Eric R ER
Bacteriophage 20110701 4
Bacteriophage-encoded proteins which inhibit or modify cellular components may contribute to antibacterial drug discovery by allowing the identification of novel targets. Given their abundance and diversity, phages may have various strategies in host inhibition and therefore may possess a variety of such proteins. Using Rhodococcus equi and phage YF1, we show that a single phage possesses numerous genes that inhibit the host when introduced into the host on a plasmid. These genes mostly encode p ...[more]