Ontology highlight
ABSTRACT:
SUBMITTER: Shimizu T
PROVIDER: S-EPMC3454391 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Shimizu Takehiko T Ho Bao B Deeley Kathleen K Briseño-Ruiz Jessica J Faraco Italo M IM Schupack Brett I BI Brancher João A JA Pecharki Giovana D GD Küchler Erika C EC Tannure Patricia N PN Lips Andrea A Vieira Thays C S TC Patir Asli A Yildirim Mine M Poletta Fernando A FA Mereb Juan C JC Resick Judith M JM Brandon Carla A CA Orioli Iêda M IM Castilla Eduardo E EE Marazita Mary L ML Seymen Figen F Costa Marcelo C MC Granjeiro José M JM Trevilatto Paula C PC Vieira Alexandre R AR
PloS one 20120924 9
There is evidence for a genetic component in caries susceptibility, and studies in humans have suggested that variation in enamel formation genes may contribute to caries. For the present study, we used DNA samples collected from 1,831 individuals from various population data sets. Single nucleotide polymorphism markers were genotyped in selected genes (ameloblastin, amelogenin, enamelin, tuftelin, and tuftelin interacting protein 11) that influence enamel formation. Allele and genotype frequenc ...[more]