Ontology highlight
ABSTRACT:
SUBMITTER: Wang CY
PROVIDER: S-EPMC3457568 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Wang Chin-Ya CY Wang Shainn-Wei SW Huang Wen-Chun WC Kim Kwang Sik KS Chang Nan-Shan NS Wang Ying-Hsiang YH Wu Meng-Hsing MH Teng Ching-Hao CH
Infection and immunity 20120723 10
Escherichia coli is a common Gram-negative organism that causes bacteremia. Prc, a bacterial periplasmic protease, and its homologues are known to be involved in the pathogenesis of Gram-negative bacterial infections. The present study examined the role of Prc in E. coli bacteremia and characterized the ability of the prc mutant of the pathogenic E. coli strain RS218 to cause bacteremia and survive in human serum. The prc mutant of RS218 exhibited a decreased ability to cause a high level of bac ...[more]